Bridion (Sugammadex) (a.k.a. Roc-Stop)
Aug 06, 2008 in Learn
Image from Wikipedia
In case you missed it, Sugammadex (a reversal agent molecularly designed to reverse Rocuronium) got it’s license approved in the EU last week…but not in the USA!
See MedicalNewsToday’s article.
So what does that mean?
Well apart from making anaesthetics very interesting in the very near future, it means that the question about reversal agents which was done badly in the April exam has a high probability of showing up again.
So here are a few links to information about it, and references to articles which you ought to read:
Safety and tolerability of single intravenous doses of sugammadex administered simultaneously with rocuronium or vecuronium in healthy volunteers
Cammu et al. Br. J. Anaesth..2008; 100: 373-379
Neuromuscular monitoring and postoperative residual curarisation: a meta-analysis
M. Naguib, A. F. Kopman, and J. E. Ensor
Br. J. Anaesth., March 2007; 98: 302 - 316.
Wikipedia Article on Sugammadex
Remember that one of the main parts of the question centred on side-effects of reversal agents, so make sure you are aware of the side effects of Glycopyrrolate-Neostigmine as well!
